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DIRECTOR OF FINANCE - JANUX THERAPEUTICS, INC. - SAN DIEGO, CA

Janux is developing unique immunotherapies that generate tumor-specific immune responses to attack and kill tumors without destroying...

PENN STATE RESEARCHERS DEVELOP A WAY TO STUDY MICROENVIRONMENT OF BREAST CANCER IN 3D

Cancerous tumors thrive on blood, extending their roots deep into the fabric of the tissue of their host. They alter the genetics of...

 
 
 

CO-ADMINISTRATION OF COMBRETASTATIN A4 NANOPARTICLES AND ANTI-PD-L1 FOR SYNERGISTIC THERAPY OF HEPATOCELLULAR CARCINOMA

According to data estimated by the WHO, primary liver cancer is currently the fourth most common malignant tumor and the second leading...

IS COMBINED RECOGNITION THE SOLUTION FOR CAR-T THERAPY AGAINST GLIOBLASTOMA, OTHER SOLID TUMORS?

Is combined recognition the solution for CAR-T therapy against glioblastoma, other solid tumors? aliu Thu, 04/29/2021 - 08:49

 
 
 
Top in hem/onc: CAR-T for diffuse midline gliomas, new endometrial cancer therapy

TOP IN HEM/ONC: CAR-T FOR DIFFUSE MIDLINE GLIOMAS, NEW ENDOMETRIAL CANCER THERAPY

Researchers recently presented early data on the efficacy of chimeric antigen receptor T-cell therapy for diffuse midline gliomas during...

TRILLIUM UNVEILS CD47 CLINICAL RESEARCH PRIORITIES AS INVESTORS AWAIT SOLID TUMOR DATA

Trillium unveils CD47 clinical research priorities as investors await solid tumor data aarmstrong Tue, 04/27/2021 - 16:32

 
 
 

HIGH EXPRESSION OF TUMOR SUSCEPTIBILITY GENE 101 IS ASSOCIATED WITH MORE AGGRESSIVE BEHAVIOR IN COLORECTAL CARCINOMA

Abstract Introduction Identification of genetic determinants such as exosomal content that drives progression and metastasis of colorectal...

A DUAL-TARGETING RUTHENIUM NANODRUG THAT INHIBITS PRIMARY TUMOR GROWTH AND LUNG METASTASIS VIA THE PARP/ATM PATHWAY

Many studies have found that ruthenium complexes possess unique biochemical characteristics and inhibit tumor growth or metastasis.

 
 
 

IMMUNOENGINEERED MAGNETIC-QUANTUM DOT NANOBEAD SYSTEM FOR THE ISOLATION AND DETECTION OF CIRCULATING TUMOR CELLS

Highly efficient capture and detection of circulating tumor cells remain elusive mainly because of their extremely low concentration...

Infliximab discontinuation links to relapse in patients with ulcerative colitis

INFLIXIMAB DISCONTINUATION LINKS TO RELAPSE IN PATIENTS WITH ULCERATIVE COLITIS

Discontinued long-term use of infliximab correlated with lower rates of maintained remission in patients with ulcerative colitis, according...

 
 
 
Phosphorus replacement, 'whole team' approach benefit patients with rare bone disorders

PHOSPHORUS REPLACEMENT, 'WHOLE TEAM' APPROACH BENEFIT PATIENTS WITH RARE BONE DISORDERS

Patients with both X-linked hypophosphatemia and tumor-induced osteomalacia can benefit from phosphorus replacement therapy, according...

For RA Elders, Is There a Better Target Than TNF?

FOR RA ELDERS, IS THERE A BETTER TARGET THAN TNF?

Older patients with rheumatoid arthritis who were treated with interleukin -6 inhibitors were less likely to stop treatment than those...

 
 
 

FACILE FABRICATION OF MULTI-POCKET NANOPARTICLES WITH STEPWISE SIZE TRANSITION FOR PROMOTING DEEP PENETRATION AND TUMOR TARGETING

Nanocarriers-derived antitumor therapeutics are often associated with issues of limited tumor penetration and dissatisfactory antitumor...

HOW BRAIN TUMORS TURN IMMUNE CELLS INTO CANCER-GROWING HOSTAGES

Researchers discover that brain cancer tumors reprogram immune cells to help them grow, rather than suppress them.

 
 
 

RAPID IMPEDANCE SPECTROSCOPY FOR MONITORING TISSUE IMPEDANCE, TEMPERATURE, AND TREATMENT OUTCOME DURING ELECTROPORATION-BASED THERAPIES

Electroporation-based therapies employ high voltage pulsed electric fields to permeabilize tumor tissue; this results in a detectable...

Molecular characteristics of early-onset colorectal cancer appear to vary by race

MOLECULAR CHARACTERISTICS OF EARLY-ONSET COLORECTAL CANCER APPEAR TO VARY BY RACE

Black patients with early-onset, microsatellite-stable colorectal cancer had substantially higher tumor mutational burden than their...

 
 
 

TANTIGEN 2.0: A KNOWLEDGE BASE OF TUMOR T CELL ANTIGENS AND EPITOPES

We previously developed TANTIGEN, a comprehensive online database cataloging more than 1000 T cell epitopes and HLA ligands from 292...

Tumor mutational burden predicts treatment response among women, not men, with melanoma

TUMOR MUTATIONAL BURDEN PREDICTS TREATMENT RESPONSE AMONG WOMEN, NOT MEN, WITH MELANOMA

Tumor mutational burden predicted immune checkpoint inhibitor response among women, but not men, with melanoma, according to findings...

 
 
 

BLUEBIRD, PSIOXUS SHOW ONCOLYTIC VIRUS BOOSTS CAR-T IN SOLID TUMORS

Bluebird, PsiOxus show oncolytic virus boosts CAR-T in solid tumors ntaylor Wed, 04/14/2021 - 08:44

MSIFINDER: A PYTHON PACKAGE FOR DETECTING MSI STATUS USING RANDOM FOREST CLASSIFIER

Microsatellite instability is a common genomic alteration in colorectal cancer, endometrial carcinoma, and other solid tumors. MSI...