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Biogen's Alzheimer's disease drug crashes in Phase III testing

BIOGEN'S ALZHEIMER'S DISEASE DRUG CRASHES IN PHASE III TESTING

The news sent Biogen's shares down more than 26 percent pre-market, but analysts also wrote that it deals a significant blow to amyloid...

IBM USES MACHINE LEARNING TO DETECT EARLY ALZHEIMER'S IN BLOOD SAMPLES

A buildup of the protein amyloid-beta in spinal fluid can predict Alzheimer's long before symptoms appear, but it's difficult to detect....

 
 
 

DYSREGULATION OF TLR5 AND TAM LIGANDS IN THE ALZHEIMER'S BRAIN AS CONTRIBUTORS TO DISEASE PROGRESSION

Abstract The hypothesis that accumulation of beta-amyloid species in the brain represents a major event in Alzheimer's disease pathogenesis...

GRAFTING A SHORT CHAMELEON SEQUENCE FROM ΑB CRYSTALLIN INTO A Β‐SHEET SCAFFOLD PROTEIN

Many protein and peptide sequences are self‐assembled into β‐sheet‐rich fibrous structures called amyloids. Their atomic details provide...

 
 
 
Tetra Inks Deal with Shionogi to Support Fragile X, Alzheimer's R&D

TETRA INKS DEAL WITH SHIONOGI TO SUPPORT FRAGILE X, ALZHEIMER'S R&D

The lead drug of Tetra Discovery Partners is already in mid-stage clinical studies as a treatment for the rare Fragile X Syndrome....

15 For '19: Key Clinical Data To Watch For Next Year

15 FOR '19: KEY CLINICAL DATA TO WATCH FOR NEXT YEAR

It can take decades and billions of dollars to develop a drug, and its fate-and often that of its developer-rests in the outcome of...

 
 
 
Eli Lilly Partners with AC Immune on Tau Blockers for Alzheimer's

ELI LILLY PARTNERS WITH AC IMMUNE ON TAU BLOCKERS FOR ALZHEIMER'S

There's at least one major pharmaceutical company that isn't giving up yet on finding an Alzheimer's disease drug. Eli Lilly is pairing...

STUNNING: Alzheimer's disease is NOT caused by amyloid plaque - the disease is multi-factorial and rooted in inflammation

STUNNING: ALZHEIMER'S DISEASE IS NOT CAUSED BY AMYLOID PLAQUE - THE DISEASE IS MULTI-FACTORIAL AND ROOTED IN INFLAMMATION

The facts about Alzheimer's disease are truly alarming: Over 5.7 million Americans have been diagnosed with this condition, and by...

 
 
 
Polyneuropathy Risk Identified in Six Biomarkers of Inflammation

POLYNEUROPATHY RISK IDENTIFIED IN SIX BIOMARKERS OF INFLAMMATION

For the first time a team of researchers have identified six biomarkers of inflammation that indicate the risk of polyneuropathy, a...

 
 
 

MIMICKING CROSS-Α AMYLOIDS

Mimicking cross-α amyloids Mimicking cross-α amyloids, Published online: 17 August 2018; doi:10.1038/s41589-018-0118-0 The design of...

New Drug Shows Promise Against Alzheimer's

NEW DRUG SHOWS PROMISE AGAINST ALZHEIMER'S

A promising new drug appears to be especially good at sopping up toxic pieces of beta amyloid protein that stick together in the brain...

 
 
 
Experimental Alzheimer's drug stirs hope after early trials

EXPERIMENTAL ALZHEIMER'S DRUG STIRS HOPE AFTER EARLY TRIALS

A drug for early-stage dementia shows promise in reducing the formation of beta-amyloid clusters, a hallmark of Alzheimer's, according...

 
 
 
Biogen, Eisai Claim Success in New Analysis of Failed Alzheimer's Study

BIOGEN, EISAI CLAIM SUCCESS IN NEW ANALYSIS OF FAILED ALZHEIMER'S STUDY

Biogen and Eisai are reporting encouraging data from a mid-stage study in Alzheimer's disease, reviving hopes for a drug and an approach...

What Causes Alzheimer's Disease may Protect from Herpes Infection

WHAT CAUSES ALZHEIMER'S DISEASE MAY PROTECT FROM HERPES INFECTION

Amyloid beta protein protects the brain from herpes infection by entrapping viral particles, research at the Massachusetts General...

 
 
 
Alzheimer's may NOT be caused by toxic protein clumps killing brain cells: Study debunks the theory

ALZHEIMER'S MAY NOT BE CAUSED BY TOXIC PROTEIN CLUMPS KILLING BRAIN CELLS: STUDY DEBUNKS THE THEORY

Unlike previous findings, researchers from the University of Queensland did not find amyloid protein plaques lead to nerve cell death...

TWO IS BETTER THAN ONE TO IMPROVE BRAIN FUNCTION IN ALZHEIMER'S DISEASE MOUSE MODEL

Using two complementary approaches to reduce the deposits of amyloid-beta in the brain rather than either approach alone improved spatial...

 
 
 
Just ONE sleepless night raises the risk of Alzheimer's disease

JUST ONE SLEEPLESS NIGHT RAISES THE RISK OF ALZHEIMER'S DISEASE

A study of 20 people, led by researchers at the National Institutes of Health in Maryland, found a night without sleep increased the...

New Blood Test for Early Detection of Alzheimer's Disease

NEW BLOOD TEST FOR EARLY DETECTION OF ALZHEIMER'S DISEASE

Alzheimer's disease can be identified at an early stage by a new blood test which measures the relative amounts of a pathological and...