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MAPPING VAST UNKNOWN TERRITORY OF LONG NON-CODING RNA

Scientists have developed a powerful method for exploring the properties of mysterious molecules called long non-coding RNAs , some...

Lasker Awards Recognize Propofol Discovery, Women in Science Advocate & Others

LASKER AWARDS RECOGNIZE PROPOFOL DISCOVERY, WOMEN IN SCIENCE ADVOCATE & OTHERS

The winners of the U.S.'s most prestigious awards in biomedical sciences were announced today, for work in developing propofol, the...

 
 
 

NEW TECHNIQUE REVEALS HOW ZIKA VIRUS INTERACTS INSIDE OUR CELLS

Scientists have developed a new technique that can determine how viruses interact with a host's own RNA. As well as providing insight...

New Look at Breast Cancer Cell Line Sheds Light on Structural Complexity

NEW LOOK AT BREAST CANCER CELL LINE SHEDS LIGHT ON STRUCTURAL COMPLEXITY

In an exciting paper that made the cover of Genome Research , scientists from Cold Spring Harbor Laboratory and collaborating institutions...

 
 
 

EPIGENOMIC AND TRANSCRIPTOMIC CHARACTERIZATION OF SECONDARY BREAST CANCERS

Abstract Background Molecular alterations impact tumor prognosis and response to treatment. This study was designed to identify transcriptomic...

A REGULATORY CIRCUITRY BETWEEN GRIA2, MIR-409, AND MIR-495 IS AFFECTED BY ALS FUS MUTATION IN ESC-DERIVED MOTOR NEURONS

Abstract Mutations in fused in sarcoma cause amyotrophic lateral sclerosis. FUS is a multifunctional protein involved in the biogenesis...

 
 
 
HIV RNA Expression Inhibitors as a Therapy to Restore Immune Function in HIV-Infected Persons

HIV RNA EXPRESSION INHIBITORS AS A THERAPY TO RESTORE IMMUNE FUNCTION IN HIV-INFECTED PERSONS

Use of HIV RNA expression inhibitors as additive therapy might reduce atypical inflammation and restore immune function in HIV-infected...

 
 
 
Bio Roundup: Big Approvals, ICER Influence, Drug-Price Pushback & More

BIO ROUNDUP: BIG APPROVALS, ICER INFLUENCE, DRUG-PRICE PUSHBACK & MORE

We'll start the roundup this week with two drug approvals that came late last Friday. Both were landmarks for the companies receiving...

GENETIC VARIANTS IN FAT‐ AND SHORT‐TAILED SHEEP FROM HIGH‐THROUGHPUT RNA‐SEQUENCING DATA

Animal Genetics, EarlyView.

 
 
 
Bio Roundup: Medicare Drug Prices, FDA Moves, Gene Therapy News & More

BIO ROUNDUP: MEDICARE DRUG PRICES, FDA MOVES, GENE THERAPY NEWS & MORE

Two imminent FDA rulings on two separate drugs aren't just noteworthy for the patients they'll help, but the long and winding road...

 
 
 

ROLE OF MIRNAS IN HYPOXIA-RELATED DISORDERS

Abstract Hypoxia is a complex pathophysiological condition. The physiological and molecular responses to this stress have been extensively...

A MULTICOLOR RIBOSWITCH-BASED PLATFORM FOR IMAGING OF RNA IN LIVE MAMMALIAN CELLS

A multicolor riboswitch-based platform for imaging of RNA in live mammalian cells A multicolor riboswitch-based platform for imaging...

 
 
 

POSTTRANSCRIPTIONAL REGULATION OF CYCLIN D1 BY ARE-BINDING PROTEINS AUF1 AND HUR IN CYCLING MYOBLASTS

Abstract RNA binding proteins can regulate the stability and/or translatability of messengerRNAs through interactions with their 3′-untranslated...

Bio Roundup: Alnylam's Moment, Read on Rebates, Skinny Plans & More

BIO ROUNDUP: ALNYLAM'S MOMENT, READ ON REBATES, SKINNY PLANS & MORE

Millions of people might be on vacation as we hit the dog days, but drug makers and politicians aren't taking a break from the gamesmanship...

 
 
 

CHANGES TO SPERM'S SMALL RNA IN THE EPIDIDYMIS MAY HELP ENSURE MOUSE EMBRYOS IMPLANT

This week, Louise Brown, the first person born after conception by in vitro fertilization , celebrates her 40th birthday. Thanks to...

MATATAKI: AN ULTRAFAST MRNA QUANTIFICATION METHOD FOR LARGE-SCALE REANALYSIS OF RNA-SEQ DATA

Data generated by RNA sequencing is now accumulating in vast amounts in public repositories, especially for human and mouse genomes....

 
 
 
Maize Collaborators Embark on Ambitious 26-line Pangenome Project

MAIZE COLLABORATORS EMBARK ON AMBITIOUS 26-LINE PANGENOME PROJECT

Computational biologist Doreen Ware harvests maize tissue for RNA isolation. Photo by Miriam Chua c/o USDA The first reference genome...

BRAINEXP: A DATABASE FEATURING WITH SPATIOTEMPORAL EXPRESSION VARIATIONS AND CO-EXPRESSION ORGANIZATIONS IN HUMAN BRAINS

AbstractMotivationGene expression changes over the lifespan and varies among different tissues or cell types. Gene co-expression also...