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DNA'S ON/OFF SWITCH

The enzyme DNA primase synthesizes the RNA primers essential to initiate the replication of our genomes.

'Major step forward' for millions of osteoarthritis patients as study discovers 52 genetic mutations

'MAJOR STEP FORWARD' FOR MILLIONS OF OSTEOARTHRITIS PATIENTS AS STUDY DISCOVERS 52 GENETIC MUTATIONS

Team led by scientists in Cambridge analysed the genomes of over 447,000 people. The research has doubled the known number of genes...

 
 
 

GENOME SEQUENCE OF BACILLUS ANTHRACIS TYPING PHAGE AP631

Abstract AP631, a virulent bacteriophage of Bacillus anthracis , is widely used in China to identify anthrax bacteria. In this study,...

RETROPHYLOGENOMICS IN RORQUALS INDICATE LARGE ANCESTRAL POPULATION SIZES AND A RAPID RADIATION

Abstract Background Baleen whales are the largest animals on earth and their evolutionary history has been studied in detail, but some...

 
 
 

STUDY ON A TWO-COMPONENT SIGNAL TRANSDUCTION SYSTEM RIMA1A2 THAT NEGATIVELY REGULATES OXYTETRACYCLINE BIOSYNTHESIS IN STREPTOMYCES RIMOSUS M4018

Abstract Biosynthesis of secondary metabolites in actinobacteria is regulated by complex regulatory mechanisms on responding environmental...

A GENOME-WIDE VIEW OF MUTATIONS IN RESPIRATION-DEFICIENT MUTANTS OF SACCHAROMYCES CEREVISIAE SELECTED FOLLOWING CARBON ION BEAM IRRADIATION

Abstract Mitochondrial dysfunction in Saccharomyces cerevisiae was selected as a marker of ion penetration following carbon ion beam...

 
 
 

HIGH FREQUENCY OF PATHOGENIC AND RARE SEQUENCE VARIANTS IN DIABETES-RELATED GENES AMONG RUSSIAN PATIENTS WITH DIABETES IN PREGNANCY

Abstract Aims Diabetes in pregnancy may be associated with monogenic defects of beta-cell function, frequency of which depends on ethnicity,...

Scientists have learned how to interrupt cancer cell growth; allowing them to prevent cancer's adaptation to treatment

SCIENTISTS HAVE LEARNED HOW TO INTERRUPT CANCER CELL GROWTH; ALLOWING THEM TO PREVENT CANCER'S ADAPTATION TO TREATMENT

It has been 16 years since the human genome was decoded - an accomplishment that scientists hoped would someday prove useful in cancer...

 
 
 
One For All: HiFi Long Reads for de Novo Assembly and Comprehensive Variant Detection

ONE FOR ALL: HIFI LONG READS FOR DE NOVO ASSEMBLY AND COMPREHENSIVE VARIANT DETECTION

CCS read protocol We're excited to report on new SMRT Sequencing advances that will ultimately help users generate extremely accurate,...

SEX INFLUENCES DNA METHYLATION AND GENE EXPRESSION IN HUMAN SKELETAL MUSCLE MYOBLASTS AND MYOTUBES

Abstract Background Sex differences are known to impact muscle phenotypes, metabolism, and disease risk. Skeletal muscle stem cells...

 
 
 

SIM1000G: A USER-FRIENDLY GENETIC VARIANT SIMULATOR IN R FOR UNRELATED INDIVIDUALS AND FAMILY-BASED DESIGNS

Abstract Background Simulation of genetic variants data is frequently required for the evaluation of statistical methods in the fields...

HERPES VIRUSES AND TUMORS EVOLVED TO LEARN HOW TO MANIPULATE THE SAME ANCIENT RNA

Herpes viral infections use the ancient genetic material found in the human genome to proliferate, mimicking the same process tumors...

 
 
 

CIRCULATING MIR-3659 MAY BE A POTENTIAL BIOMARKER OF DYSLIPIDEMIA IN PATIENTS WITH OBESITY

Abstract Background The present study attempted to identify potential key genes and miRNAs of dyslipidemia in obese, and to investigate...

ENDORNAVIRUSES: PERSISTENT DSRNA VIRUSES WITH SYMBIOTIC PROPERTIES IN DIVERSE EUKARYOTES

Abstract Endornaviruses are unique, persistent, double-stranded RNA viruses with symbiotic properties that infect diverse eukaryotes,...

 
 
 
Webinar Recap: SMRT Sequencing offers Many Advantages for Microbial Research

WEBINAR RECAP: SMRT SEQUENCING OFFERS MANY ADVANTAGES FOR MICROBIAL RESEARCH

According to many, PacBio is the new “gold standard” in microbial sequencing. Chief Scientific Officer Jonas Korlach notes that its...

MSC: A METAGENOMIC SEQUENCE CLASSIFICATION ALGORITHM

AbstractMotivationMetagenomics is the study of genetic materials directly sampled from natural habitats. It has the potential to reveal...

 
 
 

TRANSCRIPTIONAL REGULATION OF CHILLING STRESS RESPONSIVE LONG NONCODING RNAS IN POPULUS SIMONII

Abstract Key message We report genome-wide identification and functional prediction of lncRNAs under chilling stress, the present study...

COMPLETE GENOME SEQUENCE OF CAULOBACTER FLAVUS RHGG3 T , A TYPE SPECIES OF THE GENUS CAULOBACTER WITH PLANT GROWTH-PROMOTING TRAITS AND HEAVY METAL RESISTANCE

Abstract Caulobacter flavus RHGG3 T , a novel type species in the genus Caulobacter , originally isolated from rhizosphere soil of...

 
 
 

INTERNATIONAL PLANT & ANIMAL GENOME XXVII

PAG brings together over 3,000 leading genetic scientists and researchers in plant and animal research, and over 130 exhibits, 150...

NRGENE AND TOYOTA COLLABORATE TO DEVELOP STRAWBERRY VARIETIES TO BETTER ENABLE LOCAL PRODUCTION FOR THE JAPANESE MARKET

NESS ZIONA, Israel & SAN DIEGO & AICHI, Japan--lt;a href="" target=" blank"gt; AIlt;/agt;-The decoding of a leading commercial strawberry...