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96267 SINGLE CELL GENOMICS RESEARCH ASSOCIATE

CELLULAR & MOLECULAR MEDICINE Salary commensurate with qualifications and experienceFiling Deadline: Fri 11/2/2018...

How the Giraffe Got Its Spots: A Genetic Just-So Story

HOW THE GIRAFFE GOT ITS SPOTS: A GENETIC JUST-SO STORY

Spots are common in the animal kingdom. Birds, insects, reptiles, fishes, and of course mammals sport spots. In Darwinian terms, a...

 
 
 
How Companies are Using Microbiome-Based Therapies to Improve Patient Outcomes

HOW COMPANIES ARE USING MICROBIOME-BASED THERAPIES TO IMPROVE PATIENT OUTCOMES

On Wednesday morning at the BIO Investor Forum , leaders from six companies at the forefront of microbiome innovation assembled to...

PARGENES: A TOOL FOR MASSIVELY PARALLEL MODEL SELECTION AND PHYLOGENETIC TREE INFERENCE ON THOUSANDS OF GENES

AbstractMotivationCoalescent- and reconciliation-based methods are now widely used to infer species phylogenies from genomic data....

 
 
 

RESEARCHERS MODIFY CRISPR TO REORGANIZE GENOME

Researchers have reworked CRISPR-Cas9 gene-editing technology to manipulate the genome in three-dimensional space, allowing them to...

IN VITRO VERSUS IN VIVO COMPOSITIONAL LANDSCAPES OF HISTONE SEQUENCE PREFERENCES IN EUCARYOTIC GENOMES

AbstractMotivationAlthough the nucleosome occupancy along a genome can be in part predicted by in vitro experiments, it has been recently...

 
 
 
Sequel System 6.0 Release Offers a New Paradigm in DNA Sequencing: Highly Accurate Single-Molecule Long Reads

SEQUEL SYSTEM 6.0 RELEASE OFFERS A NEW PARADIGM IN DNA SEQUENCING: HIGHLY ACCURATE SINGLE-MOLECULE LONG READS

Today we're pleased to announce the release of Sequel System 6.0 , including new software, consumable reagents and a new SMRT Cell. Combined,...

GENOPRI'16: INTERNATIONAL WORKSHOP ON GENOME PRIVACY AND SECURITY

 
 
 

CRISPR-MEDIATED DELETION OF PROSTATE CANCER RISK-ASSOCIATED CTCF LOOP ANCHORS IDENTIFIES REPRESSIVE CHROMATIN LOOPS

Recent genome-wide association studies have identified more than 100 loci associated with increased risk of prostate cancer, most of...

EXPANDING FUNGAL DIVERSITY, ONE CELL AT A TIME

Researchers have developed a pipeline to generate genomes from single cells of uncultivated fungi. The approach was tested on several...

 
 
 

PHLI-SEQ: CONSTRUCTING AND VISUALIZING CANCER GENOMIC MAPS IN 3D BY PHENOTYPE-BASED HIGH-THROUGHPUT LASER-AIDED ISOLATION AND SEQUENCING

Spatial mapping of genomic data to tissue context in a high-throughput and high-resolution manner has been challenging due to technical...

Data Release: Highest-Quality, Most Contiguous Individual Human Genome Assembly to Date

DATA RELEASE: HIGHEST-QUALITY, MOST CONTIGUOUS INDIVIDUAL HUMAN GENOME ASSEMBLY TO DATE

We're proud to announce the release of the most contiguous diploid human genome assembly of a single individual to date, representing...

 
 
 

DIGREM: AN INTEGRATED WEB-BASED PLATFORM FOR DETECTING EFFECTIVE MULTI-DRUG COMBINATIONS

AbstractMotivationSynergistic drug combinations are a promising approach to achieve a desirable therapeutic effect in complex diseases...

WHOLE GENOME SEQUENCING REVEALS RARE OFF‐TARGET MUTATIONS AND CONSIDERABLE INHERENT GENETIC OR/AND SOMACLONAL VARIATIONS IN CRISPR/CAS9‐EDITED COTTON PLANTS

Plant Biotechnology Journal, Volume 0, Issue ja , -Not available-.

 
 
 
Genome Center Faculty Megan Dennis earns NIH Director's New Innovator Award

GENOME CENTER FACULTY MEGAN DENNIS EARNS NIH DIRECTOR'S NEW INNOVATOR AWARD

Megan Dennis Assistant Professor Megan Dennis has been awarded $1.5M as part of the National Institute of Health Director's New Innovator...

Sanger Institute Birthday Gift to Scientists: 25 New Wildlife Genomes to Support Conservation and Science

SANGER INSTITUTE BIRTHDAY GIFT TO SCIENTISTS: 25 NEW WILDLIFE GENOMES TO SUPPORT CONSERVATION AND SCIENCE

King scallops are more genetically diverse than we are? The Roesel's bush cricket's genome is four times the size of ours? These are...

 
 
 
Beloved Barn Swallow Gets SMRT Sequencing “Platinum Genome” Treatment

BELOVED BARN SWALLOW GETS SMRT SEQUENCING “PLATINUM GENOME” TREATMENT

With its bold blue plumage, russet throat and chipper chirps, the barn swallow is beloved by many avian enthusiasts. It's also a favorite...

 
 
 

GENOMIC AND PHENOTYPIC CHARACTERIZATION OF A REFACTORED XYLOSE-UTILIZING SACCHAROMYCES CEREVISIAE STRAIN FOR LIGNOCELLULOSIC BIOFUEL PRODUCTION

Engineered strains of Saccharomyces cerevisiae have significantly improved the prospects of biorefinery by improving the bioconversion...

Iso-Seq SMRT Grant Winner to Study Alternative Splicing in Neurons

ISO-SEQ SMRT GRANT WINNER TO STUDY ALTERNATIVE SPLICING IN NEURONS

Xiaochang Zhang, an assistant professor at the University of Chicago, is poised to get a powerful new data set to help his team understand...