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Review: How Long-Read Sequencing Could Make a Difference in Medical Genetics

REVIEW: HOW LONG-READ SEQUENCING COULD MAKE A DIFFERENCE IN MEDICAL GENETICS

A recent review article published in Frontiers in Genetics offers a great look at the landscape of long-read sequencing. Authors Tuomo...

Applications and Benefits of Single-Molecule Transcriptome Sequencing

APPLICATIONS AND BENEFITS OF SINGLE-MOLECULE TRANSCRIPTOME SEQUENCING

When looking to understand the functional implications of genetic variability, scientists should seek out the Iso-Seq method, according...

 
 
 
Researchers Find “Camouflaged” Gene Regions Key to Alzheimer's and More

RESEARCHERS FIND “CAMOUFLAGED” GENE REGIONS KEY TO ALZHEIMER'S AND MORE

Despite efforts by researchers, experts are still unable to determine a genetic basis of disease for many people diagnosed. One reason:...

SABER TECH GIVES DNA AND RNA VISUALIZATION A BOOST

Researchers have been using "Fluorescence in situ hybridization" analysis for decades to literally fish for specific DNA and RNA sequences...

 
 
 

NEUTROPHIL CYTOSOLIC FACTOR 1 CONTRIBUTES TO THE DEVELOPMENT OF SEPSIS

Abstract To identify differentially expressed genes in sepsis and potential key role of reactive oxygen species genes associated with...

Breakthrough Technique for Studying Gene Expression Takes Root in Plants

BREAKTHROUGH TECHNIQUE FOR STUDYING GENE EXPRESSION TAKES ROOT IN PLANTS

Researcher Christine Shulse tends to Arabidopsis plants in a lab at the DOE Joint Genome Institute. An open-source RNA analysis platform...

 
 
 
SMRT Leiden Symposium Showcases Successes in Clinical and Conservation Genomics

SMRT LEIDEN SYMPOSIUM SHOWCASES SUCCESSES IN CLINICAL AND CONSERVATION GENOMICS

What can a cute, cuddly, stingless bee from the Brazilian rainforest teach us about eusociality and mitochondrial evolution? Natalia...

 
 
 

MULTIPHATE: BIOINFORMATICS PIPELINE FOR FUNCTIONAL ANNOTATION OF PHAGE ISOLATES

AbstractSummaryTo address the need for improved phage annotation tools that scale, we created an automated throughput annotation pipeline:...

NEXT‐GENERATION SEQUENCING IDENTIFIED GENOMIC REGION AND DIAGNOSTIC MARKERS FOR RESISTANCE TO BACTERIAL WILT ON CHROMOSOME B02 IN PEANUT

Abstract Bacterial wilt, caused by Ralstonia solanacearum, is a devastating disease affecting over 350 plant species. A few peanut...

 
 
 

CATCH A VIRUS BY ITS TAIL

Research uncovers key mechanism that allows some of the deadliest human RNA viruses to orchestrate the precise copying of the individual...

TOMATO PAN-GENOME MAKES BRINGING FLAVOR BACK EASIER

Do you find that most store-bought tomatoes don't have much flavor? Scientists may have spotlighted the solution by developing the...

 
 
 

SCIENTISTS CREATE NEW GENOMIC RESOURCE FOR IMPROVING TOMATOES

Tomato breeders have traditionally emphasized traits that improve production, like larger fruits and more fruits per plant. As a result,...

UNDERSTANDING RELATIONSHIP BREAK-UPS TO PROTECT THE REEF

Unravelling the secrets of the relationship between coral and the algae living inside it will help prevent coral bleaching, researchers...

 
 
 

HOW WHALES DEFY THE CANCER ODDS: GOOD GENES

Scientists have studied potential cancer suppression mechanisms in cetaceans, the mammalian group that includes whales, dolphins and...

The 2019 Global Startup Ecosystem Report launches at TNW2019

THE 2019 GLOBAL STARTUP ECOSYSTEM REPORT LAUNCHES AT TNW2019

Today, on the TNW Conference Main Stage, we are delighted to help launch the 2019 Global Startup Ecosystem Report with Startup Genome....

 
 
 
Sequencing of Historical Cholera Sample Surprises Sanger Scientists

SEQUENCING OF HISTORICAL CHOLERA SAMPLE SURPRISES SANGER SCIENTISTS

They are the unwelcome comeback kids: Measles, mumps and other old-time diseases that were once nearly extinct are on the rise in suburban...

New Sequel II System Enables Rapid Characterization of Invasive Pests

NEW SEQUEL II SYSTEM ENABLES RAPID CHARACTERIZATION OF INVASIVE PESTS

USDA campaign poster to stop the spread of the invasive pest Stop, Scrape, Squash... and Sequence! The latest invasive insect to hit...

 
 
 

FREQUENCY OF OFF-TARGETING IN GENOME EDITED PIGS PRODUCED VIA DIRECT INJECTION OF THE CRISPR/CAS9 SYSTEM INTO DEVELOPING EMBRYOS

The CRISPR/Cas9 system can effectively introduce site-specific modifications to the genome. The efficiency is high enough to induce...

METABOLIC CHARACTERIZATION OF THE CHITINOLYTIC BACTERIUM SERRATIA MARCESCENS USING A GENOME-SCALE METABOLIC MODEL

Serratia marcescens is a chitinolytic bacterium that can potentially be used for consolidated bioprocessing to convert chitin to value-added...