Search

New Study Shows CRISPR Can Delete Big Chunks of DNA

NEW STUDY SHOWS CRISPR CAN DELETE BIG CHUNKS OF DNA

[ Updated 7/16/18 1:00pm ET, see note below ] As CRISPR-based therapeutics inch closer to human tests in the U.S., academic researchers...

Safety fears over revolutionary gene-editing tool Crispr/Cas9

SAFETY FEARS OVER REVOLUTIONARY GENE-EDITING TOOL CRISPR/CAS9

Wellcome Sanger Institute scientists tested the effects of Crispr on both mouse and human cells in the laboratory. The findings were...

 
 
 

FDA AIMS TO FACILITATE GENE THERAPY DEVELOPMENT FOR HEMOPHILIA, RARE DISEASES

Posted on: 13 July 2018, Significant progress has been made in gene therapy research and development over the years, with promise...

CONSTRUCTION OF A TRIFUNCTIONAL CELLULASE AND EXPRESSION IN SACCHAROMYCES CEREVISIAE USING A FUSION PROTEIN

Cellulose is the most important component of lignocellulose, and its degradation requires three different types of enzymes to act synergistically....

 
 
 

FINDING THE PROTEINS THAT UNPACK DNA

A new method allows researchers to systematically identify specialized proteins called 'nuclesome displacing factors' that unpack DNA...

PXST, A NOVEL VECTOR FOR TA CLONING AND BLUNT-END CLONING

With the rapid development of sequencing technologies, increasing amount of genomic information has been accumulated. To clone genes...

 
 
 
Maize Collaborators Embark on Ambitious 26-line Pangenome Project

MAIZE COLLABORATORS EMBARK ON AMBITIOUS 26-LINE PANGENOME PROJECT

Computational biologist Doreen Ware harvests maize tissue for RNA isolation. Photo by Miriam Chua c/o USDA The first reference genome...

EU Regulators Approve Akcea's Inotersen. FDA Decisions Are Next

EU REGULATORS APPROVE AKCEA'S INOTERSEN. FDA DECISIONS ARE NEXT

Akcea Therapeutics has beaten rival Alnylam Pharmaceuticals to a first drug approval, getting the nod for its drug inotersen in the...

 
 
 
Tango, Finch, Indigo & More: The 2018 Xconomy Award Startup Finalists

TANGO, FINCH, INDIGO & MORE: THE 2018 XCONOMY AWARD STARTUP FINALISTS

This year's bumper crop of Xconomy Award startup finalists cover a wide range of technologies and approaches, from microbiome and gene...

New Way to Non-invasively Control the Brain Discovered

NEW WAY TO NON-INVASIVELY CONTROL THE BRAIN DISCOVERED

By combining ultrasound, gene therapy, and synthetic drugs, researchers have figured out a way to noninvasively control the brain.

 
 
 

ITERATIVE CYCLE OF WIDELY TARGETED METABOLIC PROFILING FOR THE IMPROVEMENT OF 1-BUTANOL TITER AND PRODUCTIVITY IN SYNECHOCOCCUS ELONGATUS

Metabolomics is the comprehensive study of metabolites that can demonstrate the downstream effects of gene and protein regulation,...

FLUORESCENT FISH GENES LIGHT PATH TO NEUROBLASTOMA

A neurodevelopmental biologist has a new tool in the search for the origins of neuroblastoma, the third-most common pediatric cancer...

 
 
 

GENOME EDITING REDUCES CHOLESTEROL IN LARGE ANIMAL MODEL, LAYING HUMAN TRIAL GROUNDWORK

Using genome editing to inactivate a protein called PCSK9 effectively reduces cholesterol levels in rhesus macaques, a species of monkey,...

AXOVANT LICENSES BENITEC MUSCULAR DYSTROPHY DRUG, CONTINUING PIVOT TOWARD GENE THERAPIES

Axovant has picked up global rights to Benitec Biopharma's gene therapy against oculopharyngeal muscular dystrophy. The gene therapy,...

 
 
 

CROSS SPECIES TRANSFER OF GENES HAS DRIVEN EVOLUTION

Far from just being the product of our parents, University of Adelaide scientists have shown that widespread transfer of genes between...

BRAINEXP: A DATABASE FEATURING WITH SPATIOTEMPORAL EXPRESSION VARIATIONS AND CO-EXPRESSION ORGANIZATIONS IN HUMAN BRAINS

AbstractMotivationGene expression changes over the lifespan and varies among different tissues or cell types. Gene co-expression also...

 
 
 

HOW CRISPR TOOLS ARE UNLOCKING NEW WAYS TO FIGHT DISEASE

Recent leaps in gene editing technology have brought ideas that just a decade ago seemed like science fiction to the cusp of reality.

PNEUMOCOCCAL DNA PREDICTS COURSE OF INFECTION

Besides the patient's condition, pneumococcal DNA also appears to provide information about the course of an infection. Researchers...

 
 
 

CONTROLLING CRISPR AND GENE THERAPY WITH AN AMINO ACID SWITCH

Scientists in the U.K. have created a switch that controls protein expression in cultured cells and mouse embryos and could one day...

EARLY EXPRESSION OF WUSCHEL IS A MARKER FOR IN VITRO SHOOT MORPHOGENESIS IN TOBACCO AND BETA PALONGA

Abstract We have studied the role of growth regulators behind in vitro shoot organogenesis and somatic embryogenesis in two plant systems,...