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HUWE1 employs a giant substrate-binding ring to feed and regulate its HECT E3 domain

Posted on: Jul 25, 2021   |   Posted by: Biotech Mag Top

Nature Chemical Biology, Published online: 22 July 2021; doi:10.1038/s41589-021-00831-5 The full-length structure of HUWE1 reveals the bipartite organization of a giant E3...

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